Nosaki,S., Ohtsuka, M., Nakano,T., Tanokura,M., Miyakawa,T. Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain. FEBS lettershttps://doi.org/10.1002/1873-3468.70147 (2025)
Murata, T., Nakano,T., Okuro,T., Sasaki, K., Ebina,M., Asami,T. Research on the Practical Application of Grassland Plants for Restoring Degraded Grasslands and Promoting Healthy Growth of Livestock in Mongolia. Plant Genetic Resources (PGR) for Sustainable Crop Production: SATREPS Projects Tackling Global Warming and Environmental Extremes in Developing Countries, 97-106, DOI: 10.1007/978-981-96-7117-5_9 (2025)
Matsuura-Tokita, K., Suzuki,T., Kimata,Y., Takebayashi,Y., Ueda,M., Nakano,T., Sakakibara,H., Nakano,A., Higashiyama.,T. Brassinosteroids promote pollen tube guidance by coordinating gene expression in male and female reproductive tissues. Cell Reports, DOI:10.1016/j.celrep.2025.115815 (2025)
Furihata, H., Zhu, Z., Nishida, K., Sakuraba, Y., Tsuji, A., Yamashita, H., Nosaki, S., Tachibana, R., Yamagami, A., Ikeda,Y., Abe, M., Sawasaki, T., Nakano, T., Yanagisawa, S., Tanokura, M., Miyakawa, T. Structural insights into CDF1 accumulation on the CONSTANS promoter via a plant-specific DNA-binding domain. Nature Plants. 11(4):836-848. DOI: 10.1038/s41477-025-01946-6(2025)
Miyaji, T., Yamagami, A., Nakamura, Y., Nishida, K., Tachibana, R., Surina, S., Fujioka, S., Garcia‐Hourquet, M., Mora‐García, S., Nosaki, S., Miyakawa, T., Tanokura, M., Matsui, M., Osada, H., Shinozaki, K., Asami, T., Nakano, T. BIL7 enhances plant growth by regulating the transcription factor BIL1/BZR1 during brassinosteroid signaling. Plant Journal. 20 December 2024. https://doi.org/10.1111/tpj.17212 (2024)
Wang, J., Takahashi, I., Kikuzato, K., Sakai, T., Zhu, Z., Jiang, K., Nakamura, H., Nakano, T., Tanokura, M., Miyakawa, T., Asami, T. Identification and structure-guided development of triazole urea-based selective antagonists of Arabidopsis karrikin signaling. Nature Communications.16(1):104.(2024) DOI: 10.1038/s41467-024-54801-1
Namuunaa, G., Baldorj Bujin, B., Ayumi Yamagami, A.,Bolortuya, B., Kawabata, S., Ogawa, H., Kanatani, A., Shimizu, M.,Minami, A., Mochida, K., Miyakawa, T., Bekh-Ochir Davaapurev, B.,Tadao Asami, T., Javzan Batkhuu, J., Nakano, T. Identification and functional analyses of drought stress resistance genes by transcriptomics of the Mongolian grassland plant Chloris virgata. BMC Plant Biology, 25 Article Number:44 (2025) DOI: 10.1186/s12870-025-06046-3
Chagan, Z., Nakata, G., Suzuki, S., Yamagami, A., Tachibana, R., Surina, S., Fujioka, S., Matsui, M., Kushiro, T., Miyakawa, T., Asami, T., Nakano, T. BRZ-INSENSITIVE-LONG HYPOCOTYL8 inhibits kinase-mediated phosphorylation to regulate brassinosteroid signaling. Plant Physiology, kiae191, doi.org/10.1093/plphys/kiae191 (2024)
Surina, S., Yamagami, A., Miyaji, T., Chagan, Z., Chung, K., Mitsuda, N., Nishida, K., Tachibana, R., Zhu, Z., Miyakawa, T., Shinozaki, K., Sakuta, M., Asami, T., Nakano, T. BIL9 Promotes Both Plant Growth via BR Signaling and Drought Stress Resistance by Binding with the Transcription Factor HDG11. Plant and Cell Physiology pcae009, doi.org/10.1093/pcp/pcae009 (2024)
Shibata, K., Moriizumi, H., Onomoto, K., Kaneko, Y., Miyakawa, T., Zenno, S., Tanokura, M., Yoneyama, M., Takahashi, T., Ui-Tei, K. Caspase-mediated processing of TRBP regulates apoptosis during viral infection. Nucleic Acids Research 52 (9), 5209-5225 (2024)
Ohashi-Ito, K., Iwamoto, K., Yamagami, A., Nakano, T., Fukuda, H. HD-ZIP III-dependent local promotion of brassinosteroid synthesis suppresses vascular cell division in Arabidopsis root apical meristem. PNAS, 120(15):e2216632120. doi: 10.1073/pnas.2216632120. (2023)
Saito M, Momiki R, Ebine K, Yoshitake Y, Nishihama R, Miyakawa T, Nakano T, Mitsuda N, Araki T, Kohchi T, Yamaoka S. A bHLH heterodimer regulates germ cell differentiation in land plant gametophytes.Curr Biol.33(22):4980-4987.e6. doi: 10.1016/j.cub.2023.09.020. (2023)
Nishikawa, B., Mori, K., Takimoto, S., Watanabe, B., Matsuo, M., Nakano, T., Nakagawa, Y., Miyagawa, H. Quantitative evaluation of the biological activity of various brassinosteroids using spiral root induction in rice seeds. Journal of Pesticide Science 48(4) 218-224. https://doi.org/10.1584/jpestics.D23-044. (2023)
Hashimoto, T., Hashimoto, K., Shindo, H., Tsuboyama, S., Miyakawa, T., Tanokura, M., Kuchitsu, K. Enhanced Ca2+ binding to EF-hands through phosphorylation of conserved serine residues activates MpRBOHB and chitin-triggered ROS production. Physiologia Plantarum 175 (6), e14101 (2023)
Takeda, H., Ozawa, T., Zenke, H., Ohnuki, Y., Umeda, Y., Zhou, W., Tomoda, H., Takechi, A., Narita, K., Shimizu, T., Miyakawa, T., Ito, Y., Sawasaki, T. VNAR development through antigen immunization of Japanese topeshark (Hemitriakis japanica). Frontiers in Bioengineering and Biotechnology 11, 1265582 (2023)
Yamanaka, S., Furihata, H., Yanagihara, Y., Taya, A., Nagasaka, T., Usui, M., Nagaoka, K., Shoya, Y., Nishino, K., Yoshida, S., Kosako, H., Tanokura, M., Miyakawa, T., Imai, Y., Shibata, N., Sawasaki, T. Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation. Nature Communications 14 (1), 4683 (2023)
Nozawa, A., Miyazaki, R., Aoki, Y., Hirose, R., Hori, R., Muramatsu, C., Shigematsu, Y., Nemoto, K., Hasegawa, Y., Fujita, K., Miyakawa, T., Tanokura, M., Suzuki, S., Sawasaki, T. Identification of a new gibberellin receptor agonist, diphegaractin, by a cell-free chemical screening system. Communications Biology 6 (1), 448 (2023)
Kidokoro, S., Konoura, I., Soma, F., Suzuki, T., Miyakawa, T., Tanokura, M., Shinozaki, K., Yamaguchi-Shinozaki, K. Clock-regulated coactivators selectively control gene expression in response to different temperature stress conditions in Arabidopsis. PNAS, 120 (16), e2216183120 (2023)
Wang, Y., Takano, T., Zhou, Y., Wang, R., Toshimitsu, T., Sashihara, T., Tanokura, M., Miyakawa, T., Nakajima-Adachi, H., Hachimura, S. Orally administered Lactiplantibacillus plantarum OLL2712 decreased intestinal permeability, especially in the ileum: Ingested lactic acid bacteria alleviated obesity-induced inflammation by collaborating with gut microbiota. Frontiers in Immunology 14, 1123052 (2023)
Nosaki, S., Mitsuda, N., Sakamoto, S., Kusubayashi, K., Yamagami, A., Xu, Y., Bui, T. B. C., Terada, T., Miura, K., Nakano, T., Tanokura, M., Miyakawa, T. Brassinosteroid-induced gene repression requires specific and tight promoter binding of BIL1/BZR1 via DNA shape readout. Nature Plants, 8 (12), 1440-1452 (2022)
Tachibana, R., Yamagami, A., Miyagi, S., Nakazawa-Miklasevica, M., Matsui, M., Sakuta, M., Tanaka, R., Asami, T., Nakano, T. BRZ-INSENSITIVE-PALE GREEN 1 is encoded by chlorophyll biosynthesis enzyme gene that functions in the downstream of brassinosteroid signaling. Bioscience, Biotechnology, and Biochemistry, 86 (8), 1041-1048 (2022)
Takimoto, S., Nishikawa, B., MAtsuo, M., Hinata, S., Hisatomi, T., Yamagami, A., Nakano, T., Nakagawa, Y., Miyagawa, H. Structure modification of nonsteroidal brassinolide-like compound, NSBR1. Bioscience, Biotechnology, and Biochemistry, Volume 86, Issue 8, August 2022, Pages 1004–1012, (2022)
Hasesawa,R., Fujita, K., Tanaka, Y., Ikeda, M., Yamagami, A., Mitsuda, N., Nakano, T., Ohme-Takagi, M. Arabidopsis zinc finger homeodomain transcription factor BRASSINOSTEROID-RELATED HOMEOBOX 2 acts as a positive regulator of brassinosteroid response. Plant Biotechnology, 39 (2) Pages 185.
Hasesawa,R., Arakawa, T., Fujita, K., Tanaka, Y., Ookawa, Zen., Sakamoto, S., Takasaka, H., Ikeda, M., Yamagami, A., Mitsuda, N., Nakano, T., Ohme-Takagi, M. Arabidopsis homeobox-leucine zipper transcription factor BRASSINOSTEROID-RELATED HOMEOBOX 3 regulates leaf greenness by suppressing BR signaling. Plant Biotechnology, 39 (2) Pages 209-214. (2022)
Imaizumi K, Nishimura T, Nagao R, Saito K, Nakano T, Ishikita H, Noguchi T, Ifuku K (2022) D139N mutation of PsbP enhances the oxygen-evolving activity of photosystem II through stabilized binding of a chloride ion. PNAS Nexus. 1: pgac136
Takeuchi K, Che Y, Nakano T, Miyake C, Ifuku K. The ability of P700 oxidation in photosystem I reflects chilling stress tolerance in cucumber. J. Plant Res. 135: 681–692 (2022)
Kumazawa M, Nishide H, Nagao R, Inoue-Kashino N, Shen JR, Nakano T, Uchiyama I, Kashino Y, Ifuku K., Molecular phylogeny of fucoxanthin-chlorophyll a/c proteins from Chaetoceros gracilis and Lhcq/Lhcf diversity.Physiol Plant Jan;174(1):e13598. doi: 10.1111/ppl.13598. (2022)
Miyakawa, T., Yang, J., Kawasaki, M., Adachi, N., Fujii, A., Miyauchi, Y., Muramatsu, T., Moriya, T., Senda, T., Tanokura, M. Structural bases for aspartate recognition and polymerization efficiency of cyanobacterial cyanophycin synthetase. Nature Communications, 13 (1), 5097 (2022)
Wang, R., Nakajima-Adachi, H., Wang, Y., Zhou, Y., Gu, W., Hiraide, E., Morinaga, M., Nakagawa, R., Nakamura, S., Takano, T., Li, X., Saeki, M., Kaminuma, O., Hiroi, T., Uchida, K., Motoshima, H., Tanokura, M., Miyakawa, T., Hachimura, S. Regulation of Th2 responses by Lactococcus lactis subsp. cremoris YRC3780 alleviates DNCB-induced atopic dermatitis in the mouse model. Journal of Functional Foods, 94, 105091 (2022)
Zhou, Y., Takano, T., Li, X., Wang, Y., Wang, R., Zhu, Z., Tanokura, M., Miyakawa, T., Hachimura, S. β-elemene regulates M1-M2 macrophage balance through the ERK/JNK/P38 MAPK signaling pathway. Communications Biology, 5 (1), 519 (2022)
Negishi, K., Aizawa, K., Shindo, T., Suzuki, T., Sakurai, T., Saito, Y., Miyakawa, T., Tanokura, M., Kataoka, Y., Maeda, M., Tomida, S., Morita, H., Takeda, N., Komuro, I., Kario, K., Nagai, R., Imai, Y. An Myh11 single lysine deletion causes aortic dissection by reducing aortic structural integrity and contractility. Scientific Reports, 12 (1), 8844 (2022)
Embaby, H. E., Miyakawa, T., Hachimura, S., Muramatsu, T., Nara, M., Tanokura, M. Physical and chemical properties of nabak (Zizyphus spina‐christi) seed kernel and sweet pepper (Capsicum annuum L.) seed oils. Journal of the Science of Food and Agriculture, 102 (7), 2660-2666 (2022)
2021
Bolortuya, B., Kawabata, S., Yamagami, A., Davaapurev, B., Takahashi, F., Inoue, K., Kanatani, A., Mochida, K., Kumazawa, M., Ifuku, K., Jigjidsuren, S., Battogtokh, T., Udval, G., Shinozaki, K., Asami, T., Batkhuu, J., Nakano, T. Transcriptome analysis of Chloris virgata, which shows the fastest germination and growth in the major Mongolian grassland plant. Front Plant Sci., Jun 28;12:684987. doi: 10.3389/fpls.2021.684987. (2021)
Nosaki S, Terada T, Nakamura A, Hirabayashi K, Xu Y, Bui TBC, Nakano T, Tanokura M, Miyakawa T. Highlighting the potential utility of MBP crystallization chaperone for Arabidopsis BIL1/BZR1 transcription factor-DNA complex. Sci Rep. 2021 Feb 16;11(1):3879. (2021)
Nagao R, Yokono M, Ueno Y, Suzuki T, Kumazawa M, Kato KH, Tsuboshita N, Dohmae N, Ifuku K, Shen JR, Akimoto S., Enhancement of excitation-energy quenching in fucoxanthin chlorophyll a/c-binding proteins isolated from a diatom Phaeodactylum tricornutum upon excess-light illumination. Biochim Biophys Acta Bioenerg. https://doi.org/10.1016/j.bbabio.2020.148350, 2021 Feb 1;1862(2):148350. (2021)
2020
Sako, K., Futamura, Y., Shimizu, T., Matsui, A., Hirano, H., Kondoh, Y., Muroi, M., Aono, H., Tanaka, M., Honda, K., Shimizu, K., Kawatani, M., Nakano, T., Osada, H., Noguchi, K., Seki, M. Inhibition of mitochondrial complex I by the novel compound FSL0260 enhances high salinity-stress tolerance in Arabidopsis thaliana. Scientific Reports 10, Article number: 8691(2020)
Nakamura-Yamaguchi, A., Kitahata, N., Nishitani, C., Takada, N., Terakami, S., Sawamura, Y., Matsuyama, T., Asami, T., Nakano, T., Saito, T., Yamamoto, T. Pattern and trigger of fruit self-thinning in Japanese pears. The Horticulture Journal, UTD-177(2020)
Ishikawa, N., Yokoe, Y., Nishimura, T., Nakano, T., Ifuku, K. PsbQ-like protein 3 functions as an assembly factor for the chloroplast NADH dehydrogenase-like complex in Arabidopsis. Plant Cell Physiol. 2020 Apr 25. pii: pcaa050. doi: 10.1093/pcp/pcaa050. (2020)
Che, Y., Kusama, S., Matsui, S., Suorsa, M., Nakano, T., Aro, EM., Ifuku, K. Arabidopsis PsbP-like protein 1 facilitates the assembly of the photosystem II supercomplexes and optimizes plant fitness under fluctuating light. Plant Cell Physiol. 2020 Apr 11. pii: pcaa045. doi: 10.1093/pcp/pcaa045. (2020)
Nagao, R., Kato, K., Ifuku, K., Suzuki, T., Kumazawa,M., Uchiyama, I., Kashino, Y., Dohmae, N., Akimoto, S., Shen, J.-R., Miyazaki, N. Akita, F. Structural basis for assembly and function of a diatom photosystem I-light harvesting supercomplex. Nature Commun. 11: 2481. (2020)
Ifuku, K. and Nagao, R. “Evolution and Function of the Extrinsic Subunits of Photosystem II”, In: “Photosynthesis: Molecular Approaches to Solar Energy Conversion” (eds: J-R. Shen, K. Satoh, S. I., & Allakhverdiev) Springer Nature, Dordrecht, The Netherlands, (2020)
Nakano, T. Hypocotyl elongation: A molecular mechanism for the first event in plant growth that influences its physiology. Plant Cell Physiol. 1;60(5):933–934. (2019)
Yoshida, K., Kondoh, Y., Iwahashi, F., Nakano, T., Honda, K., Nagano, E., Osada, H. Abscisic acid derivatives with different alkyl chain lengths 2 activate distinct abscisic acid receptor subfamilies. ACS Chemical Biology, 14(9), 1964–1971 (2019)
Itoh, K., Kashino, Y., Ifuku, K., Maeda, K., Yamamoto, T. Taguchi, S. Dispersed air flotation of microalgae using venturi tube type microbubble generator. Biomass and Bioenergy 130: 105379. (2019)
Nagao, R., Kato, K., Suzuki, T., Ifuku, K., Uchiyama, I., Kashino, Y., Dohmae, N., Akimoto, S., Shen, J.-R., Miyazaki, N.,
Akita, F. Structural basis for energy harvesting and dissipation in a diatom PSII-FCPII supercomplex. Nature Plants 5:890–901. (2019)
Takagi, D., Ifuku, K., Nishimura, T., Miyake, C. Antimycin A inhibits cytochrome b559 -mediated cyclic electron flow within photosystem II. Photosynth. Res. 139: 487–498. (2019)
Ifuku, K., Yan, D. “Efficient Transformation of the Diatoms Phaeodactylum tricornutum by Multi-Pulse Electroporation” In: Methods in Molecular Biology “Electroporation Protocols” (eds: S., Li, L. Chang, & J., Teissie) Springer Nature, Dordrecht, The Netherlands, ISBN 9781493997398. (2019)
Nosaki, S., Miyakawa, T., Xu, Y., Nakamura, A., Hirabayashi, K., Asami, T., Nakano, T., Tanokura, M. Structural basis for brassinosteroid response by BIL1/BZR1. Nature Plants, 4, 771–776 (2018)
Jaroensanti-Tanaka, N., Miyazaki, S., Hosoi, A., Tanaka, K., Ito, S., Iuchi, S., Nakano, T., Kobayashi, M., Nakajima, M., Asami, T. The chemical NJ15 affects hypocotyl elongation and shoot gravitropism via cutin polymerization. Biosci. Biotechnol. Biochem. 82(10):1770–1779. (2018)
Nakano, T., Tanaka, S., Ohtani, M., Yamagami, A., Takeno, S., Hara, N., Mori, A., Nakano, A., Hirose, S., Himuro, Y., Kobayashi, M., Kushiro, T., Demura, T., Asami, T., Osada, H., Shinozaki, K. FPX is a novel chemical inducer that promotes callus formation and shoot regeneration of plant. Plant Cell Physiol. 59, 1555–1567 (2018)
Yamagami, A., Saito, C., Nakazawa, M., Fujioka, S., Uemura, T., Matsui, M., Sakuta, M., Osada, H., Nakano, A., Asami, T., Nakano, T. Brassinosteroids regulate vacuolar morphology in root meristem cells of Arabidopsis thaliana. Plant Signal and Behavior 13, e1417722 (2018)
Fujiwara, M., Yasuzawa, M., Kojo, K.H., Niwa, Y., Abe, T., Yoshida, S., Nakano, T., Itoh, R. The Arabidopsisarc5 and arc6 mutations differentially affect plastid morphology in pavement vs. guard cells in the leaf epidermis. PLoS ONE., Feb 21, 2018 (2018)
Shimakawa, G., Ifuku, K., Suzuki, Y., Makino, A., Ishizaki, K., Fukayama, H., Morita, R., Sakamoto, K., Nishi, A., Miyake, Responses of the chloroplast glyoxalase system to high CO2 concentrations. Biosci. Biotechnol. Biochem. 82: 2072-2083 (2018)
Asada, M., Nishimura, T., Ifuku, K., Mino, H. Location of the extrinsic subunit PsbP in photosystem II studied by pulsed electron-electron double resonance. Biochim. Biophys. Acta (Bioenergetics) 1859: 394–399. (2018)
高木大輔、伊福健太郎，「アンチマイシン A が引き起こす光化学系 II 内部のシトクロム b559 への阻害効果」，光合成研究, 28(2), 82–93 (2018)
2017
Yamagami, A., Saito, C., Nakazawa, M., Fujioka, S., Uemura, T., Matsui, M., Sakuta, M., Osada, H., Nakano, A., Asami, T., Nakano, T. Evolutionarily conserved BIL4 interacts with the brassinosteroid receptor BRI1 and regulates cell elongation. Scientific Reports 7(1) Article number 5739 (2017)
Sugiura, A., Horoiwa, S., Aoki, T., Takimoto, S., Yamagami, A., Nakano, T., Nakagawa, Y., Miyagawa, H. Discovery of a nonsteroidal brassinolide-like compound, NSBR1. Journal of Pesticide Science42 (3), 105–111 (2017) (日本農薬学会論文賞)
Fujiwara, M., Yasuzawa, M., Sasaki, S., Nakano, T., Niwa, Y., Yoshida, S., Abe, T., Itoh, R. The Arabidopsis minD mutation causes aberrant FtsZ1 ring placement and moderate heterogeneity of chloroplasts in the leaf epidermis. Plant Signal. Behav. Jul 3;12(7):e1343776 (2017)
Jiang, K., Shimotakahara, H., Luo, M., Otani, M., Nakamura, H., Moselhy, S.S., Abualnaja, K.O., Al-Malki, A.L., Kumosani, T.A., Kitahata, N., Nakano, T., Nakajima, M., Asami, T. Chemical screening and development of novel gibberellin mimics. Bioorganic & Medicinal Chemistry Letters 27, 3678–3682 (2017 )
Ueda, M., Egoshi, S., Dodo, K., Ishimaru, Y., Yamakoshi, H., Nakano, T., Takaoka, Y., Tsukiji, S., Sodeoka, M. Noncanonical function of a small-molecular virulence factor coronatine against plant immunity: An In Vivo raman imaging approach. ACS Central Science. 3, 462–472 (2017)
Thussagunpanit, J., Jutamanee, K., Homvisasevongsa, S., Suksamrarn, A., Yamagami, A., Nakano, T., Asami, T. Characterization of synthetic ecdysteroid analogues as functional mimics of brassinosteroids in plant growth. J Steroid Biochem Mol Biol. 172, 1–8 (2017)
Nakamura, A., Tochio, N., Fujioka, S., Ito, S., Kigawa, T., Shimada, Y., Matsuoka, M., Yoshida, S., Kinoshita, T., Asami, T., Seto, H., Nakano, T. Molecular actions of two synthetic brassinosteroids, iso-carbaBL and 6-deoxoBL, which cause altered physiological activities between Arabidopsis and rice. PLoS ONE. April 3 (2017)
Jiang, K., Otani, M., Shimotakahara, H., Yoon, J-M., Park, S-H., Miyaji, T., Nakano, T., Nakamura, H., Nakajima, M., Asami, T. Substituted phthalimide AC94377 is a selective agonist of the gibberellin receptor GID1. Plant Physiology 173, 825–835 (2017)
Nishimura, T., Sato, F., Ifuku, K. In vivo system for analyzing the function of the PsbP protein using Chlamydomonas reinhardtii. Photosynth. Res. 133: 117–127. (2017)
Endo, Y., Hatanaka, T., Maeda, K., Arafune, K., Yamamoto, T., Itoh, K., Kuramochi, H., Kashino, Y., Ifuku, K. Use of ethanol with triolein for fatty acid ethyl ester as biodiesel fuel in a Novozym® 435 fixed-bed reactor. Biomass and Bioenergy 108: 433–438. (2017)
伊福健太郎 「光化学系 II 表在性タンパク質の分子進化と酸素発生における役割」, 光合成研究, 27(3), 191–200 (2017)
